The single chain receptors constitute another pleiotropic family that plays an important role in hematopoietic and non hematopoietic tissue.
This includes the receptors for GH(growth hormone), EPO (erythropoietin), PRL (prolactin), TPO (thrombopoeitin). The single chain receptors signal predominantly through activation of JAK2 and STAT5 pathways.
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Source::Optimized DNA sequence encoding HumanProlactin mature chain was expressed in Escherichia Coli. Molecular weight::Human Prolactin is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculated mole -
Source::Optimized DNA sequence encoding HumanTPO erythropoeitin domain was expressed in Chinese Hamster Ovary cells. Molecular weight:: Native Human TPO, generated by the proteolytic removal of the signal peptide and propeptide,and has a calculated
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Source::Optimized DNA sequence encoding mouse TPO erythropoeitin like domain was expressed in Escherichia Coli. Molecular weight:: Native mouse TPO, generated by the proteolytic removal of the signal peptide and propeptide,The molecule has a calcula
