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Rabbit anti CD79a (IGBP1) Polyclonal

CD79

accession:  P11912
   Size A     100ug   $ 190
   Size B      200ug  $290
   Size C      500ug  $ 490
Clone  : 
Isotype  :  IgG
Catalog no. :  RPA11912
Applications:
Elisa: Use at a concentration range of  1-2ug/ml.
il-2 elisa Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml.
il-2 elisa IHC: A suitable range of concentrations of this antibody for IHC  is 2-10 µg/ml.
 
CD79 IHC

Immunohistochemical analysis of CD79 expression in paraffin fixed mouse inguinal lymphoma tissue.

Cat#RPA11912 was used as primary antibody.

CD79 IHC

Immunohistochemical analysis of CD79 expression in paraffin fixed mouse intra abdominal lymphoma tissue. 

Cat#RPA11912 was used as primary antibody.

 
Source:
Polyclonal CD79a antibody was produced from sera of rabbits  immunized with synthetic protein containing CD79a antigenic determinants. 
 
Species reactivity:
Human,Mouse,Rat
 
Purification:

Serum IgG fraction was purified by Protein G affinity chromatography.

 
Presentation:
Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml.
 
Reconstitution:
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
 
Storage:
The lyophilized antibody is stable for at least 1 year  from date of receipt at -20° C.
Upon reconstitution, this antibody can be stored in working aliquots at 2° - 8° C for one month, or at -20° C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.

 
Usage:

This antibody product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

 

CD79

CD79 is a dimeric transmembrane protein that is associated with membrane immunoglobulin and initiates B-cell signaling following engagement of the latter by antigen.1-3 The 2 component chains of CD79, referred to as CD79a and CD79b. CD79a as well as CD79b is purported to be a B cellspecific antigen. CD79a expression begins at the earliest pro-B stage of development and continues throughout Bcell differentiation to the plasma cell stage,6 making it one of the most useful panB-cell markers used in routine immunophenotypic analysis. In addition, CD79a expression seems to be restricted to B-lineage cells (ie,a diagnostically specific B-cell marker).

Related Publications:
b cell depletion with anti-CD79 mabs ameliorates autoimmune disease in mrl/lpr mice
J. Immunol., Sep 2008; 181: 2961 - 2972.
antibody-drug conjugates targeted to CD79 for the treatment of non-hodgkin lymphoma
Blood, Jul 2007; 110: 616 - 623.
antibody-drug conjugates targeted to CD79 for the treatment of non-hodgkin’s lymphoma.
Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 2524.
CD79 alpha/CD79 beta heterodimers are expressed on pro-b cell surfaces without associated mu heavy chain
Int. Immunol., Nov 1997; 9: 1767 - 1772.




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Cytokines
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by species:
Human
mouse
Rat
Antibodies:
Purified Polyclonal
Related Products:
product_icon_7.jpg Rabbit anti CD79a (IGBP1) Polyclonal
 
 
 
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