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Rabbit Anti IL-28B Polyclonal

IL-28

accession:  Q8IZI9
   Size A     100ug   $ 290
   Size B      200ug  $390
   Size C       $
Clone  : 
Isotype  :  IL28B
Catalog no. :  RPAQ8IZI9
Applications:
il-2 elisa Elisa: Use at a concentration range of  1-2ug/ml.
il-2 elisa Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml.
 
 
Source:
Polyclonal Interleukin-28B antibody was produced from sera of rabbits  immunized with synthetic protein containing C- terminal Interleukin-28B antigenic determinants. 
 
Species reactivity:
Human,Mouse
 
Purification:

Serum IgG fraction was purified by Protein G affinity chromatography.

 
Presentation:
Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml.
 
Reconstitution:
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
 
Storage:
The lyophilized antibody is stable for at least 1 year  from date of receipt at -20° C.
Upon reconstitution, this antibody can be stored in working aliquots at 2° - 8° C for one month, or at -20° C for six months without detectable loss of activity. 

Avoid repeated freeze/thaw cycles.

 
Usage:

This antibody product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

IL28B

Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Related Publications:
association between the IL28B genotype and hepatitis c viral kinetics in the early days of treatment with pegylated interferon plus ribavirin in hiv/hcv co-infected patients with genotype 1 or 4
J. Antimicrob. Chemother., Jan 2012; 67: 202 - 205.
IL28B rs12979860 genotype and spontaneous clearance of hepatitis c virus in a multi-ethnic cohort of injection drug users: evidence for a supra-additive association
The Journal of Infectious Disease, Dec 2011; 204: 1843 - 1847.
predictors of sustained virological response after antiviral therapy for chronic hepatitis c in patients with hemophilia: the role of the interleukin-28b (IL28B) polymorphism
Blood (ASH Annual Meeting Abstracts), Nov 2011; 118: 2276.
genetic polymorphism in IL28B is associated with spontaneous clearance of hepatitis c virus genotype 4 infection in an egyptian cohort
The Journal of Infectious Disease, Nov 2011; 204: 1391 - 1394.
genetic polymorphism in IL28B is associated with spontaneous clearance of hepatitis c virus genotype 4 infection in an egyptian cohort
The Journal of Infectious Disease, Nov 2011; 204: 1391 - 1394.




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Antibodies:
Purified Polyclonal
Related Products:
product_icon_8.jpg Human IL-28B Recombinant
product_icon_7.jpg Rabbit Anti IL-28B Polyclonal
 
 
 
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