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Human Phospholipid Transfer Protein Recombinant


accession:  P55058
   Size A     20ug   $ 160
   Size B      100ug  $550
   Size C      500ug  $ 1950
Domain  : 
Gene  :  EPCR
Catalog no. :  RKP55058



Optimized DNA sequence encoding Human Phospholipid Transfer Protein -PLTP (VAL18 - VAL493) mature chain including a C-terminal His tag was expressed in HEK293 cells.

Molecular weight:

Recombinant Human Phospholipid Transfer Protein(PTLP) is a protein consisting of 482 amino acid residue subunits,due to glycosylation migrates as an approximately as 35kDa band protein on reduced SDS-PAGE.

>95%, as determined by SDS-PAGE and HPLC
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Recombinant human Phospholipid Transfer Protein (Lipid transfer protein II) is lyophilized  from 0.2 μm filtered PBS solution,  pH7.2 ,  5% Trehalose.

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Recombinant Human PLTP can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to -70°C for twelve months.

Avoid repeated freeze/thaw cycles.

This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.


Phospholipid Transfer Protein

Plasma phospholipid transfer protein (PLTP) binds and transfers a number of amphipathic compounds, including phospholipids, unesterified cholesterol, diacylglycerides, lipopolysaccharides, and vitamin E. It has been implicated in several biological processes, including the production and catabolism of very-low- density and low-density lipoproteins and the remodeling of high-density lipoproteins. Overall, PLTP expression was found to result in a higher incidence and faster progression of atherosclerosis in animal models, and increased expression of PLTP was most frequently associated with an increased risk of cardiovascular disease in humans

Related Publications:
Phospholipid Transfer Protein is expressed in cerebrovascular endothelial cells and involved in high density lipoprotein biogenesis and remodeling at the blood-brain barrier
J. Biol. Chem., Feb 2014; 289: 4683 - 4698.
cathepsin g degradation of Phospholipid Transfer Protein (pltp) augments pulmonary inflammation
FASEB J, Feb 2014; 10.1096/fj.13-246843.
identification of a plasmodium falciparum Phospholipid Transfer Protein
J. Biol. Chem., Nov 2013; 288: 31971 - 31983.
liver-specific Phospholipid Transfer Protein deficiency reduces high-density lipoprotein and non–high-density lipoprotein production in mice
Arterioscler Thromb Vasc Biol, Sep 2013; 33: 2058 - 2064.
the role of Phospholipid Transfer Protein (pltp) in lipoprotein metabolism in the retina
Invest. Ophthalmol. Vis. Sci., Jun 2013; 54: 1374.

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Growth factors
CD markers
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Purified Polyclonal
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