//Human CXCR4 Recombinant

Human CXCR4 Recombinant

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$160.00$1,950.00

SKU: RKP61073 Tags: , , , , , , , , , , , ,

Description

Accession
P61073
Source
Optimized DNA sequence encoding extracellular domain of Human CXCR4 MET1 -SER46) including a N-terminal IgG1 Fc tag was expressed in HEK293 cells.
Molecular weight
Recombinant human CXCR4 is a protein consisting of 390 amino acid residue subunits,due to glycosylation migrates as an approximately 45kDa protein on reduced SDS-PAGE.
Purity
>95%, as determined by SDS-PAGE and HPLC
Endotoxin
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
Presentation
Recombinant Human CXCR4 is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Storage
Recombinant CXCR4 can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.
Interactor
P51681
Interactor
Q99523
Biological Process
Molecular function
Molecular function

Methods

MPLA-activated tDCs acquire secondary lymphoid homing capacity in response to CCR7 and CXCR4 ligands compared to non-activated tDCs.

  • MPLA activation of tDCs induces upregulation of migratory receptors CCR7 and CXCR4 and enhances chemotactic responsiveness to their ligands CCL19 and CXCL12.
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