//Human TNFR2 Recombinant (CD120b)

Human TNFR2 Recombinant (CD120b)

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$350.00$1,950.00

SKU: RKP20333 Tags: , , , , , , , , , , ,

Description

Accession
P20333
Source
Optimized DNA sequence encoding extracellular domain of Human TNF receptor type 2 (TNFR2) including a C-terminal 6His tag was expressed in HEK293 cells.
Molecular weight
Recombinant human TNF receptor 2 (CD120b) is a protein consisting of248 amino acid residue subunits,due to glycosylation migrates as an approximately 45kDa protein on SDS-PAGE.
Purity
>95%, as determined by SDS-PAGE and HPLC
Biological Activity
Recombinant Human TNF receptor 2 (CD120b) activity was determined by the ability to inhibit the TNFα mediated cytotoxicity in the L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.2-0.8 μg/mL in the presence of 0.15 ng/mL recombinant Human TNFα .
Presentation
Recombinant human TNFR2 (TNFRSF1B) is supplied as a 0.2 μm filtered PBS solution,pH7.2.
Storage
Recombinant Human TNF receptor 2 (CD120b), as supplied, can be stored in working aliquots at 2° - 8° C for one month, or at -20°C to-70°Cfor twelve months. Avoid repeated freeze/thaw cycles.
Usage
This product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.
Interactor
Interactor
Interactor
Q12933
Interactor
P39429
Interactor
Q9BQ06
Molecular function
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