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Rabbit anti Death Receptor 5 Polyclonal

DR5(CD262)

accession:  P25445
   Size A     100ug   $ 230
   Size B      200ug  $340
   Size C      500ug  $ 520
Clone  : 
Isotype  :  IgG
Catalog no. :  RPA25445
Applications:
Elisa: Use at a concentration range of  1-2ug/ml.
il-2 elisa Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml.
il-2 elisa IHC: A suitable range of concentrations of this antibody for IHC  is 2-10 µg/ml.
 
Source:
Polyclonal anti-Death Receptor 5(CD262)antibody was produced from sera of rabbits immunized with synthetic protein containing DR5(262) antigenic determinants.
 
Species reactivity:
Human,Mouse,Rat
 
Purification:

Serum IgG fraction was purified by Protein G affinity chromatography.

 
Presentation:
Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml.
 
Reconstitution:
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
 
Storage:
The lyophilized antibody is stable for at least 1 year  from date of receipt at -20° C.
Upon reconstitution, this antibody can be stored in working aliquots at 2° - 8° C for one month, or at -20° C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.

 
Usage:

This antibody product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

 

Death Receptor 5



Related Publications:
the synthetic cannabinoid win 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (trail)-induced apoptosis by activating p8/ccaat/enhancer binding protein homologous protein (chop)/Death Receptor 5 (dr5) axis
Mol. Pharmacol., May 2010; 77: 854 - 863.
targeting a novel n-terminal epitope of Death Receptor 5 triggers tumor cell death
J. Biol. Chem., Mar 2010; 285: 8953 - 8966.
chm-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated Death Receptor 5 up-regulation
J. Biol. Chem., Feb 2010; 285: 5497 - 5506.
a phase i safety and pharmacokinetic study of the Death Receptor 5 agonistic antibody pro95780 in patients with advanced malignancies
Clin. Cancer Res., Feb 2010; 16: 1256 - 1263.
rottlerin induces apoptosis via Death Receptor 5 (dr5) upregulation through chop-dependent and pkc -independent mechanism in human malignant tumor cells
Carcinogenesis, May 2009; 30: 729 - 736.




by class:
Cytokines
Chemokines
Growth factors
CD markers
Viral Antigens
Other
by species:
Human
mouse
Rat
Antibodies:
Purified Polyclonal
Related Products:
product_icon_7.jpg Rabbit anti Death Receptor 5 Polyclonal
 
 
 
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