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Rabbit anti IGF-II Polyclonal

IGF-II

accession:  P01344
   Size A     100ug   $ 190
   Size B      200ug  $290
   Size C      500ug  $ 490
Clone  : 
Isotype  :  IgG
Catalog no. :  RPA01344
Applications:
Elisa: Use at a concentration range of  1-2ug/ml.
il-2 elisa Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml.
il-2 elisa IHC: A suitable range of concentrations of this antibody for IHC  is 2-10 µg/ml.
 
IGF2 IHC

Immunohistochemical analysis of IGF-II expression in human ovarian vascular endothelial cells.

Cat# RPA01344 was used as primary antibody, dilution 1:200.

 
IGF2 IHC

Immunohistochemical analysis of IGF-II expression in human breast carcinoma tissue.

Cat# RPA01344 was used as primary antibody, dilution 1:200.

 
Source:
Polyclonal IGF-II antibody was produced from sera of rabbits  immunized with synthetic protein containing IGF-2  antigenic determinants. 
 
Species reactivity:
Human,Mouse,Rat
 
Purification:

Serum IgG fraction was purified by Protein A affinity chromatography.

 
Presentation:
Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml.
 
Reconstitution:
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
 
Storage:
The lyophilized antibody is stable for at least 1 year  from date of receipt at -20° C.
Upon reconstitution, this antibody can be stored in working aliquots at 2° - 8° C for one month, or at -20° C for six months without detectable loss of activity.

Avoid repeated freeze/thaw cycles.

 
Usage:

This antibody product is for research purposes only.It may not be used for therapeutics or diagnostic purposes.

 

IGF-II

IGF-1 and IGF-2 are members of a protein family of related proteins with hormonal activities including nerve growth factor.Cell types responding to the two IGF factors include adipocytes, chondrocytes, epithelial cells, fibroblasts, glial cells, hepatocytes, muscle cells, and osteoblasts. The IGF-2 receptor, CD222, is a single-chain protein of 250 kDa. It is a high affinity binding protein for IGF-2 and shows very low affinity for IGF-1 and none for insulin. The cytoplasmic domain of the receptor does not possess intrinsic tyrosine kinase activity.

Related Publications:
cell surface-bound il-1 is an upstream regulator of the senescence-associated il-6/IL-8 cytokine network
PNAS, Sep 2009; 10.1073/pnas.0905299106.
the angiogenic effect of probiotic bacillus polyfermenticus on human intestinal microvascular endothelial cells is mediated by IL-8
Am J Physiol Gastrointest Liver Physiol, Sep 2009; 10.1152/ajpgi.00204.2009.
IL-8 signaling does not mediate intra-amniotic lps-induced inflammation and maturation in preterm fetal lamb lung
Am J Physiol Lung Cell Mol Physiol, Sep 2009; 297: L512 - L519.
the functional significance behind expressing two IL-8 receptor types on pmn
J. Leukoc. Biol., Sep 2009; 86: 529 - 543.
IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells
J. Immunol., Aug 2009; 183: 2159 - 2166.




by class:
Cytokines
Chemokines
Growth factors
CD markers
Viral Antigens
Other
by species:
Human
mouse
Rat
Antibodies:
Purified Polyclonal
Related Products:
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